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Liothyronine sodium hydrate
CAS No. 345957-19-9
Liothyronine sodium hydrate( —— )
Catalog No. M35769 CAS No. 345957-19-9
Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 34 | Get Quote |
|
| 25MG | 50 | Get Quote |
|
| 50MG | 71 | Get Quote |
|
| 100MG | 99 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLiothyronine sodium hydrate
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NoteResearch use only, not for human use.
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Brief DescriptionLiothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities.
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DescriptionLiothyronine sodium hydrate is an active form of thyroid hormone.Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
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In VitroLiothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects.
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetTHR
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RecptorThyroid hormone receptor(THR)
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Research Area——
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Indication——
Chemical Information
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CAS Number345957-19-9
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Formula Weight
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Molecular FormulaC15H11NNaO4 xH2O
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Purity>98% (HPLC)
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Solubility——
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SMILESIC(C=C(C=C1I)C[C@H](N)C([O-])=O)=C1OC2=CC(I)=C(C=C2)O.[Na+].O xH2O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94.?
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