Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - THR - Liothyronine sodium hydrate

Liothyronine sodium hydrate

CAS No. 345957-19-9

Liothyronine sodium hydrate( —— )

Catalog No. M35769 CAS No. 345957-19-9

Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 34 Get Quote
25MG 50 Get Quote
50MG 71 Get Quote
100MG 99 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Liothyronine sodium hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Liothyronine sodium hydrate (Triiodothyronine sodium hydrate) is a TRα and TRβ agonist and a thyroxine analog with anticancer and antitumor activities.
  • Description
    Liothyronine sodium hydrate is an active form of thyroid hormone.Liothyronine sodium hydrate is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
  • In Vitro
    Liothyronine (T3, 100 nM) sodium hydrate stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed. Liothyronine sodium hydrate binds to human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine sodium hydrate promotes growth, induces differentiation and regualtes metabolic effects.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    THR
  • Recptor
    Thyroid hormone receptor(THR)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    345957-19-9
  • Formula Weight
  • Molecular Formula
    C15H11NNaO4 xH2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    IC(C=C(C=C1I)C[C@H](N)C([O-])=O)=C1OC2=CC(I)=C(C=C2)O.[Na+].O xH2O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lin KH, et al. Stimulation of proliferation by 3,3',5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells overexpressing beta 1 thyroid hormone receptor. Cancer Lett. 1994 Oct 14;85(2):189-94.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Triiodothyronine Sul...

    Triiodothyronine Sulfate is a prodrug to the Conventional Hormone Therapy of Hypothyroidism.

  • TR antagonist 1

    TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TRα and TRβ, respectively) that can be used to study diseases caused by endocrine abnormalities.

  • Sobetirome

    Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).

Sign In Join Free